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“[The commerce clause was written] in the horse-and-buggy age ... since that time … we have developed an entirely different philosophy. ... We are interdependent, we are tied in together. And the hope has been that we could, through a period of years, interpret the interstate commerce clause of the Constitution in the light of these new things that have come to the country. It has been our hope that under the interstate commerce clause we could recognize by legislation and by judicial decision that a harmful practice in one section of the country could be prevented on the theory that it was doing harm to another section of the country. That was why the Congress for a good many years, and most lawyers, have had the thought that in drafting legislation we could depend on an interpretation that would enlarge the constitutional meaning of interstate commerce to include not only those matters of direct interstate commerce, but also those matters which indirectly affect interstate commerce.”

~ Franklin D. Roosevelt

Source: May 31, 1935 press conference, responding to a Supreme Court decision that defined the commerce clause narrowly enough to interfere with his regulation of farm products

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